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Medisip research group 

Medisip is a research group of the Department of Electronics and Information Systems (ELIS) of the Faculty of Engineering at the Ghent University.

Medisip's research can be subdivided in four major branches, all in the field of medical image and signal processing of which only the first two have a direct link to the institute for neuroscience:

1. Neuroscience lab

2. Infinity (Small Animal Imaging)

3. Software lab

4. Hardware lab

1. Neuroscience Lab

A major research line of Medisip is to investigate brain functionality through imaging and signal processing. This research enables the investigation of the mechanism of action of deep brain stimulation through simultaneous neuroimaging and electrophysiological recording. 

Some examples of imaging and signal processing in Neuroscience are:

▪ Advanced PET and SPECT image processing

▪ Functional magnetic resonance imaging (fMRI) statistical image processing

▪ White matter fibre tracking using Diffusion Tensor Imaging

▪ Biomedical signal processing of electroencephalographies (EEGs), event-related potentials (ERPs) and electrocardiography (ECGs)

2. Infinity 

Infinity is the preclinical imaging research facility of Ghent University, providing multimodality-imaging services to national and international customers. It is a consortium of two major research groups: Medisip and the Laboratory for Radiopharmacy. A skilled and experienced scientific staff is running Infinity. Professors Christian Vanhove, Stefaan Vandenberghe, Filip De Vos and Roel Van Holen work together to streamline the research at Infinity. Additionally, professor Christian Vanhove is also responsible for the day-to-day functioning of the lab and the coordination of the partner research, either from within Ghent University, from private companies or from other universities. The major research domains of Infinity are neuromodulation (deep brain stimulation and trans-cranial magnetic stimulation), the use of imaging biomarkers to provide better tumor characterization, stress of the endoplasmatic reticulum (er stress), cardiovascular research to get a better understanding of the formation of aneurysms and plaque, and the development of 'theranostic' approaches by combining diagnosis and therapy.

But Infinity is about more than providing service to partners. The lab is actively involved in the Multidisciplnary Research Platform on Inflammation and Immunity, called Group-ID. In 5 years time, Group-ID aims to be an international center of excellence in inflammation research, continuously attracting the best students and postdocs, have sufficient independent funding from the government and industry and become a core center of translational research in medicine.

3. Software lab

• Advanced image reconstruction for CT, PET, SPECT and MRI

• Modeling and Monte Carlo simulation of CT, PET and SPECT scanners

• Multimodal image analysis

• Investigation of metrics for the objective assessment of image quality

4. Hardware lab

• Detector design and development for PET and SPECT

• SPECT collimator design

• System design for CT scanners

• Coil design for MRI

• Phantoms for quality control in multimodal imaging

• Prototype PET and SPECT scanner development


Medisip is a research group of iMinds and works closely together with the following UGent research groups:

• "Image Processing and Interpretation" (IPI)

• "WIreless and CAble" (WICA)

• "Centre for X-Ray Tomography" (UGCT)

• "Biofluid, Tissue and Solid Mechanics for Medical Applications" (Biommeda)


Internationally, Medisip has collaborations with, amongst others:

  • University of Arizona
  • University of Massachusetts Medical School
  • University of Pennsylvania
  • University Medical Center Leiden
  • TU Delft
  • Université Lille 3

Medisip is member of HYCT (dr. E. Van Steenkiste), a valorization consortium from Ghent University. This consortium constantly monitors the valorization potential of our research. As a result, our research group has filed several patents over the past years.


Laboratory of Radiopharmacy

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